Pain Hustlers is a 2023 American crime drama film directed by David Yates from a screenplay by Wells Tower, based on the 2022 book of the same name by Evan Hughes, which tells the inside story of a band of entrepreneurial upstarts (Insys Therapeutics) who made millions selling painkillers—until their scheme unraveled, putting them at the center of a landmark criminal trial. The film stars Emily Blunt, Chris Evans, Andy García, Catherine O'Hara, Jay Duplass, Brian d'Arcy James, and Chloe Coleman. Its plot centers on a high school dropout who lands a job with a failing pharmaceutical company in Central Florida, where she soon finds herself at the center of a criminal conspiracy.