The San Francisco 49ers will travel on a short week as they face the New Orleans Saints in an NFL pro football game on Sunday afternoon. Kick off time from New Orleans is scheduled for 4:25PM Eastern Time with national television coverage provided by FOX.

The betting odds opened up in this NFL game with the road team San Francisco 49ers favored by -1 point with an over under line of 49 points. Early money has shown on the side of the home club as the game is now lined at a pick. The total has moved up a ½ point to a current total of 49 ½ points. With the game lined at a pick a money line play on either the San Francisco 49ers or New Orleans Saints will return -110 odds.

The teams last met in the NFC divisional round playoffs last year with San Francisco earning the 36-32 home win against the Saints as a +3 ½ point underdog. The total came in at over 47 points. NFL Trend: The over is 3-0-1 in their past four head to head meetings.

San Francisco improved to 7-2-1 on the season after a 32-7 home win on Monday Night Football last week against the Chicago Bears as a -3 ½ point betting favorite. The over under landed over 34 ½ points. The 49ers put up 353 yards of offense with 121 coming from their run game on 29 rushes. They had no turnovers and took two away from Chicago. Colin Kaepernick hit on 16 of 23 passes for 243 yards with two touchdowns. On the season Kaepernick has two touchdowns and no picks. Former starting quarterback Alex Smith will serve as the backup according to media reports. San Francisco allowed Chicago just 143 yards of offense with 85 from their ground attack on 28 attempts. The 49ers hold a two game lead in the loss column over the Seattle Seahawks in the NFC West with six games left to play. The 49ers are the number two defense in all of football allowing 277 yards per game. On offense they rush for 165 yards per game which is best in all of football. New Orleans have had trouble in the past defending this type of attack.

The Saints have won three straight and five of their past six games and sit at 5-5 on the season. They come off the 38-17 road win against the Oakland Raiders last week as a -6 point betting favorite. The game landed under 55 ½ points. New Orleans stormed out to the 28-7 lead in the third quarter to put the game away. Their offense put up 380 yards with 151 from their run game on 28 runs from scrimmage. They had no turnovers and force two from Oakland. Drew Brees hit on 20 of 27 passes for 219 yards with three touchdowns. On the year Brees has 28 touchdowns and nine picks. New Orleans allowed the Raiders 404 offensive yards with 120 running the football on 26 tries. The Saints are a longhshot to win the division four games back of Atlanta with six to play.