The San Francisco Giants will conclude their three game series with the Pittsburgh Pirates in a Major League Baseball game set for Wednesday afternoon. br br First pitch from Pittsburgh is scheduled for 12:30PM Eastern Time with national television coverage provided by the MLB Extra Innings channel. br br The MLB odds from this game have the home side Pittsburgh Pirates favored by -128 odds with the return on the road underdog San Francisco Giants at +118 odds. The run total is lined at seven runs.