Smoking and Cholesterol are close friends br going synergy with lung cancer br and the heart diseases, br equip their hands with knives and guns br to threat, hit and shoot br and lead the gentry to knock br on the doors of mortality. br br The off-springs of the smokers br tumble at the gate of morbidity br due to second-hand smoke br and their cognitive skills br go down with scarce oxygen. br br Nicotine gallops the rate of heart-beat br and gives a red-carpet welcome to stress in men br but reduces the beats to enhance B.P in women. br The smokers are at the risk of cardiac-crisis br and the depression leads them to be at cancer-risk br with declining strength of killer-cells, br who move with surveillance cameras br for detecting the perilous cancers.