Most fish oil consumers obtain only a fraction of an optimal dose because they take what is shown on the label. For a low quality fish oil you should take between 5-10 softgels of fish oil daily to get the most healthy dose. br br Pharmaceutical grade fish oil supplements such as those from Doctor's Holistic Rx contain a greater percentage of omega 3 fatty acids. You can take just two softgels of pharmaceutical grade fish oil daily to get the most healthy dose of omega 3 fatty acids.