Depression Quotes Image collection by Brain Quotes. br br br The WHO has declared depression as one of the most important disorder of the world in this century. Depression affects nearly one out of five girls and one out of ten guys in their life at some point. People with depression keep distance from others and slowly start feeling lonely. They could not do anything useful during the day other than worrying about their current situation or about their past experience. br br Various studies have suggested that the most severe form which is clinical depression is found more frequent among common people.