Most LGV cases are in gay men living with HIV. It is often diagnosed at the same time as another sexually transmitted infection or blood-borne disease. br br Lymphogranuloma venereum (LGV) is an uncommon sexually transmitted disease (STD) caused by Chlamydia trachomatis. ... LGV is a subtype of genital ulcer diseases that include other STDs, such as HSV-2 syphilis and chancroid. Patients with LGV may also present with rectal ulcerations .