Materials Studio is a software that provides powerful tools for molecular modeling and simulation of materials. This tutorial will teach you how to design a nanosheet from scratch using Materials Studio. Nanosheets are thin, two-dimensional nanoscale structures with a high surface area-to-volume ratio. They have unique properties that make them useful for various applications, such as graphene. This tutorial will cover the steps involved in creating a nanosheet using Materials Studio, including selecting the appropriate material, determining crystal structure, and manipulating molecular dynamics. The tutorial suits those interested in computational materials science, materials engineering, and computational chemistry. By the end of the tutorial, you will have a deeper understanding of how to design nanoscale structures and how to use Materials Studio for molecular modeling and simulation.