Shameless Season 1 Episode 3 - Shameless S01E03br br Shameless is an American soap opera television series developed by John Wells that aired on Showtime from January 9, 2011, to April 11, 2021. It is an adaptation of Paul Abbott's British series of the same name and features an ensemble cast led by William H. Macy and Emmy Rossum. The series is set in the South Side of Chicago, Illinois.