In the 2009 ICC Champions Trophy group match between India and Pakistan at Centurion on September 26, 2009, Mohammad Yousuf played a pivotal role in Pakistan's victory. After early setbacks, Yousuf partnered with Shoaib Malik to form a formidable 206-run fourth-wicket partnership. Yousuf contributed a crucial 87 runs, while Malik scored 128, leading Pakistan to a total of 302 for 9. India, in response, was bowled out for 248, resulting in a 54-run win for Pakistan.