They identified one of the mechanisms by which exercise prevents the transition from acute to chronic pain, protecting the body from inflammation and persistent pain.br br Activation of the P2X4 signaling pathway in macrophages triggers the chronicity of inflammatory muscle pain.br br Exercise prevents activation of this pathway, hence helping to prevent acute muscle pain from becoming chronic.br br In general, exercise reduces pain by:br * Promoting the release of happy chemicals like endorphins & serotonin and improving mood.br * Improving circulation.br * Reducing inflammation.br * Building muscle strength to reduce pressure on joints.br * Enhancing joint lubrication.br br General Joint structurebr From internal to external a joint typically contains:br -Articulate cartilage surfacing the articulating bones.br -Synovial fluid.br -Synovial membrane.br -Joint capsule.br -Ligaments.br -Tendons.br br How is synovial fluid produced?br Synovial fluid is produced when ultrafiltrate (primarily composed of collagen, hyaluronic acid, lubricin, & prostaglandins (a hormone-like fatty acid)), produced by blood vessels lining the joint capsule, is pushed through the synovial membrane into the joint.br br Synovial fluid lubricates and nourishes the articulate cartilage.br br Exercises improves movement and circulation of synovial fluid within the joint.br This lubricates the joints, enhances nutrient delivery, & waste removal, improving overall joint health.