Hunter with a Scalpel is a Korean drama about Seo Se Hyun, a brilliant but troubled forensic pathologist with antisocial personality disorder. She discovers a murder case during an autopsy that eerily mirrors her father's past as a serial killer, a father she believed to be dead. The series explores her struggle to reconcile her past, her profession, and the potential return of her monstrous father, all while dealing with a detective who is closing in on her. The show is a psychological thriller with elements of crime and horror, delving into dark family ties and the consequences of past actions.