How to use Xenical:br Use Xenical as directed by your doctor. Check the label on the medicine for exact dosing instructions.br br * An extra patient leaflet is available with Xenical . Talk to your pharmacist if you have questions about this information.br * Take Xenical by mouth with or up to 1 hour after each main meal that contains fat (up to 3 per day).br * If a meal is missed or contains no fat, do not take a dose of Xenical.br * You should take a multivitamin supplement containing vitamins A, D, E, and K to ensure good nutrition. The supplement should be taken at least 2 hours before or after you take Xenical , such as at bedtime.br * If you miss a dose of Xenical , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.