- Pamela Mirante and her br br development team have been working since 2008 to develop br br this extraordinary blend of ingredients including br br Satiereal Saffron Extract to help encourage permanent br br weight loss with a non-stimulant appetite suppressant. Dr. br br Oz calls this Saffron based ingredient the Miracle br br Appetite Supplement. Pamela was working to develop this br br fully-tested product years before Dr. Oz mentioned it.