Set in the fictional city of Llanview, Pennsylvania One Life to Live (OLTL) continually centers on the wealthy Lord ( Erika Slezak) family, the middle-class Woleks (Judith Light), the Rileys (Lee Patterson), and the Grays (Ellen Holly). The show has been called the most peculiarly American of soap operas: the first serial to present a vast array of ethnic types, broad comic situations, a constant emphasis on social issues and the first interracial relationship. br br (1968 - 2012) ABC Television br br (2013) The Online Network br br (2001 - 2013) bMelissa Archerb as Natalie Balsom Buchanan Laurence Vega Banks br br en.wikipedia.orgwikiOneLifetoLive br br hulu.