Bindra started working in Bollywood when she was 18 years old. Bindra has done roles in Hum Sab Ek Hai later in movies like Gadar, and many other stage shows. Her recently released films include Tara Rum Pum, Mummji, Dhan Dhana Dhan Goal and Krazzy 4.

Dolly Bindra was known for creating scenes in Big Boss reality show where she was a contestant, and Dolly was the cause of many fights in the show. She also went against Veena Malik publicly denouncing her appearance on a reality show on Colors TV. Bindra went to Pakistan at one point and she made it a point to demean Veena Malik in Lahore, Pakistan. Bindra had at one point raised her shoe in front of the Pakistani media to express her views about Veena Malik. In one of the controversies, she had accused Shweta Tiwari of giving sexual favours for Rs. 75000 and threatened her to disclose the names of the fathers of her children. She had openly accused Ashmit Patel of filming a controversial sex MMS with the Indian actress Riya Sen.