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Jose dos Santos, Jr., began his teaching career in 1958 as a full-time adjunct professor in the Department of Restorative Dentistry at the University of Sao Paulo, Brazil. Then in 1982 he accepted a joint appointment as full-time Associate Professor in Dentistry and Instructor at the Clinic of Orofacial Pain in the Department of Occlusion at the University of Michigan Dental School in Ann Arbor and in 1990 served as a full Professor in the Division of Occlusion at the University of Texas Health Science Center in San Antonio until retiring in 2003.